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Senior Biopharmaceutical Scientist

London, UK

Job Type

Full Time

Workspace

On-Site

About the Role

This position will focus on overseeing all operations within PentaBind’s wet-laboratory. The role will be responsible for the design and development of both a SELEX and a proprietary aptamer selection pipeline, in the context of an early-stage AI drug discovery company. The SELEX pipeline will be an integral part of our AI-wet-lab feedback loop. The position may also offer outstanding opportunities to work on state-of-the-art high-throughput platforms, automation and other biophysical studies. This role is ideally suited for a motivated experimental scientist who is passionate about pharmaceuticals and technology.

Key Responsibilities

  • Design, execute, and troubleshoot biochemistry and molecular biology experiments

  • Perform and optimise SELEX experiments, NGS and RT-PCR

  • Perform and develop our proprietary aptamer selection workflow

  • Suggest your own ideas, formulate plans and strategy proposals to present to the CTO and senior management

  • Maintain excellent documentation of laboratory work

  • Analyse, interpret, and present results to present to colleagues in regular meetings

  • Collaborate with the R&D ML and Bioinformatics teams

  • Maintain laboratory operations, stock control, SOP management, and regulatory compliance

  • Help shape the hiring strategy for the R&D team, train or supervise future employees

Ideal Candidate

  • Have obtained, or currently finishing, a Ph.D degree in a relevant discipline 

  • 4+ years industry experience

  • Hands-on experience with aptamer selection (e.g., SELEX) 

  • Experience in molecular biology, biochemistry, and/or assay development

  • Hands-on experience with PCR, nucleic acid QC, protein QC (e.g., SDS-PAGE) and analysis

  • English language speaking, listening and writing fluency

  • Excellent organisational, data-archiving and presentation skills 

Desired Candidate

  • Experienced in biophysical characterisation of nucleic acid-protein or nucleic acid-ligand interactions (e.g., BLI, ELISA, FP) is a plus 

  • Experienced in protein purification techniques

  • Publication in a major scientific journal with molecular biology/biochemistry contributions is a plus

About the Company

Read more about PentaBind, our culture and what to expect via the button below.

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