About the Role
This position will focus on the design and development of a SELEX pipeline in the context of an early-stage AI drug discovery company. The SELEX pipeline will be an integral part of our AI-wet-lab feedback loop. The position may also offer outstanding opportunities to work on state-of-the-art high-throughput platforms, automation and other biophysical studies. This role is ideally suited for a motivated experimental scientist who is passionate about pharmaceuticals and technology.
Key Responsibilities
Design, execute, and troubleshoot biochemistry and molecular biology experiments
Perform and optimise SELEX experiments, NGS and RT-PCR
Suggest your own ideas, formulate plans and strategy proposals to present to the CTO and senior management
Maintain excellent documentation of laboratory work
Analyse, interpret, and present results to present to colleagues in regular meetings
Collaborate with the R&D ML and Bioinformatics teams
Ideal Candidate
Have obtained, or currently finishing, a Ph.D degree in a relevant disciplineÂ
Outstanding experimental (i.e., lab) skills with an attention to detailÂ
Experience in molecular biology, biochemistry, and/or assay development
DNA and protein handling skillsÂ
Hands-on experience with PCR, nucleic acid QC, protein QC (e.g., SDS-PAGE) and analysis
English language speaking, listening and writing fluency
Excellent organisational, data-archiving and presentation skills
Desired Candidate
1+ years industry experience
Hands-on experience with aptamer selection (e.g., SELEX)Â
Experienced in biophysical characterisation of nucleic acid-protein or nucleic acid-ligand interactions (e.g., BLI, ELISA, FP) is a plusÂ
Experienced in protein purification techniques
Publication in a major scientific journal with molecular biology/biochemistry contributions is a plusÂ
About the Company
Read more about PentaBind, our culture and what to expect via the button below.