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AI Powered Aptamer Design

Unlock Your Potential with Precision Aptamer Solutions in 2024

We design aptamers that work

Our goal is to empower the aptamer industry to help society. We understand that to make a commercially viable aptamer-product you need more than just aptamer binding affinity. Using our AI and integrated wet-laboratory platform we design high-performance aptamers with all the characteristics needed to get a product on the market.

#1

PentaBind's AI platform designs aptamers with multiple characteristics in one step

Binding Affinity

Site targeting

Specificity

Stability

Conformational Folding

Additional characteristics in development

>50% improved performance in 50% less time

Our proprietary AI-based platform applies a powerful Generative AI approach to rapidly design aptamers that have a higher performance when compared to aptamers developed in physical laboratory experiments such as SELEX.
 

#2

Our AI identifies poor binders and creates completely new, higher performing aptamers

Our AI is highly creative and can generate completely new sequences not seen before in any training dataset. The process is much more powerful than bioinformatics analysis which can only select binders based upon abundance from an existing dataset of aptamer sequences.

#3

Predicted Affinity Score Distributions.jpg

#4

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Reducing the search space to improve success rates

Our AI reduces the aptamer search space from

1,298,074,214,633,706,907,132,624,082,305,024 (4^55)

to

17,179,869,184 (4^17) candidate sequences to find you better aptamers

(assuming an aptamer sequence of 55 nucleotides)

PentaBind supported us to find aptamers with higher binding affinity compared to the original [manually designed] sequences and did this in less than half the time and cost of manual experiments"

PentaBind customer

Services

Aptamer
Evaluation

Use AI to quickly test the performance an aptamer from your laboratory or from an academic paper. Receive results within 48 hours.

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Aptamer
Design

Tell us your target and requirements and we'll design a high-performance aptamer for you.

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Services for organisations with aptamer SELEX data:

SELEX
Analysis

Use AI to definitively confirm if your SELEX experiment was successful. Traditional bioinformatics tools might be missing high-performance aptamers in your SELEX data.

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Optimised
SELEX Libraries

PentaBind provides optimised and customised aptamer libraries for your SELEX pipeline.

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Contact Us

Address

Scale Space, 58 Woodlane, White City, London, United Kingdom, W12 7RZ

Contact

  • LinkedIn

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