About the Role
This position will offer the right candidate opportunities to shape our chemistry strategy and work on the design and development of aptamer selection pipelines, in the context of an early-stage AI drug discovery company. The selection pipelines are an integral part of our AI-wet-lab feedback loop. The position may also offer outstanding opportunities to work on state-of-the-art high-throughput platforms, automation and other biophysical studies. This role is ideally suited for a motivated experimental scientist who is passionate about pharmaceuticals and technology.
Key Responsibilities
Design, execute, and troubleshoot biochemistry and molecular biology experiments
Perform and optimise SELEX experiments, NGS and RT-PCR
Perform and develop our proprietary aptamer selection workflow
Support chemistry strategy
Maintain excellent documentation of laboratory work
Analyse, interpret, and present results to present to colleagues in regular meetings
Collaborate with the R&D ML and Bioinformatics teams
Minimum Requirements
Have obtained, or currently finishing, a Ph.D degree in chemistry or a relevant disciplineÂ
Experience with oligonucleotides
Experienced in molecular biology, biochemistry, and/or assay development
Hands-on experience with PCR, nucleic acid QC, protein QC (e.g., SDS-PAGE) and analysis
English language speaking, listening and writing fluency
Excellent organisational, data-archiving and presentation skillsÂ
'Nice to Have' Requirements
Experienced in biophysical characterisation of nucleic acid-protein or nucleic acid-ligand interactions (e.g., BLI, ELISA, FP) is a plusÂ
1+ years industry experience or in partnership with industry (e.g., startup, Pharma)
Publication in a major scientific journal with molecular chemistry/biology/biochemistry contributions is a plus
About the Company
Read more about PentaBind, our culture and what to expect via the button below.