Multiple Challenges, One Solution
At PentaBind, we believe that intelligent molecular targeting is essential to solving some of the world’s most urgent challenges across medicine, BioTech, CleanTech, and beyond.
That’s why we built the first synergetic AI architecture, combining our 16 Gen-AI models with a fully integrated wet-lab to create Functional Aptamers™.
We harness our synergistic AI to pursue life-changing therapeutics in oncology, and to empower visionary partners with the molecular tools they need to transform their industries and the world.
Unprecedented Design
Our aptamers do more than bind. They combine multiple functional characteristics in one molecule, unlocking possibilities traditional modalities can’t reach.
Our aptamers bind with high affinity to complex targets, forming the foundation of programmable molecular interaction.
Our aptamers are designed not only to bind selectively, but to not bind to what they shouldn’t, ensuring unmatched molecular precision.
We program our aptamers to bind at specific sites, whether on a protein, or small molecule.
Engineered for structural stability, our aptamers remain functional in extreme biological and industrial environments.
We leverage aptamer folding to enable advanced applications like conformational switching, biosensing, and real-time hormone monitoring.
PentaBind allowed us to find exceptional aptamers with higher binding affinity compared to the manually designed sequences, and did this in less than half the time and cost of manual experiments.
Our Services
We offer a suite of AI-Powered services designed to unlock precision, speed and opportunities, no matter your field.
At the heart of our services is our next-generation Functional Aptamer™ Design, built to solve the challenges that traditional approaches can’t.
Functional Aptamer™ Design
Tell us your target, we’ll design the aptamer.
PentaBind delivers a shortlist of high-performance, de novo aptamers tailored to your application, from diagnostics and therapeutics to bioprocessing and beyond. Our AI Architecture surpasses traditional SELEX workflows by optimising for binding, specificity, conformational folding, and other functionalities critical to your success.
Our Other Services
Aptamer Evaluation
Submit an aptamer, get performance insights within 48 hours.
PentaBind rapidly evaluates binding strength, specificity, isoform selectivity, SELEX bias, and more - saving time and resources in your development process.
SELEX Analysis
Validate your SELEX results with AI-powered certainty.
PentaBind analyses your submitted SELEX data to uncover enrichment patterns, bias, and overlooked high-performance sequences, ensuring nothing valuable is missed.
SELEX Libraries
Supercharge your SELEX with AI-optimised libraries.
PentaBind delivers customised libraries that reduce your search space and uncover up to 300x more candidates - accelerating aptamer discovery in your own lab.
Our Pipeline
Only 15% of the proteome has been drugged.
And 90% of marketed drugs are small molecules.
Most diseases are called “undruggable” simply because small molecules cannot bind to them quite effectively.
We are here to bridge that gap.
Trusted By
