Our company

The team closing the gap between promise and performance.

The potential of aptamers has long exceeded their real-world performance. PentaBind was built to close that gap with application-ready assets engineered and validated for sensing.

The Vision

Why we built PentaBind

Rory didn't start in aptamer design, he started as the customer they kept failing.

100 days

from target to application-ready asset

300×

more high-affinity hits

10+ characteristics

modelled across data spanning 800+ proteins

A diagnostics company

Ten years ago, Rory built a diagnostics company on aptamers.

A supply model that kept failing

Externally sourced aptamers often bound in buffer but failed under application-relevant conditions.

The exit

Rory spent six years building the company before successfully exiting.

An industry-wide problem

The bottleneck extended beyond one supplier or target. PentaBind was built to solve it systematically.

We've sat in the same seat as our clients.

Hardware, supply chains across China and London, the fundraising, the full scope of building a biosensor company, lived, not studied. That's the difference when you license from us.

A perspective no one else in aptamers has.

Most suppliers have only ever worked in the lab. We've been the customer, the builder, and the operator.

In buffer binder

Proof-of-concept or simple publication.

SenseReady

Commercially viable aptamer engineered since the beginning.

Built the hardware

Designed and shipped real diagnostic devices, not just molecules.

Ran the supply chains

Built manufacturing and supply across Shenzhen and London.

Lived the fundraise

Knows the technology and capital challenges partners face firsthand.

Closed-loop AI + wet lab

A compounding data advantage competitors can't replicate.

Built for product development. Not just molecular discovery.

Not a molecule that only performs in buffer.

Not a sequence that still needs years of optimisation.

Not a laboratory success waiting to become a commercial success.

A SenseReady™ Asset is developed towards the requirements of a sensing product: the intended matrix, the required clinical range, repeatable sensing performance and integration into the sensor platform.